Yes, its safety when used as a food additive has been approved by the U.S. Food and Drug Administration (FDA), European Food Safety Authority (EFSA), Joint FAO/WHO Expert Committee on Food Additives (JECFA), as well as other authorities.

FDA

The FDA has deemed that polydextrose may be safely used in accordance with current good manufacturing practices as a bulking agent, formulation aid, humectant, and texturizer in all foods, except meat and poultry, baby food, and infant formula. (8)

EFSA

Polydextrose (E1200) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and categorized as “additives other than colours and sweeteners” (9)

Authorised Uses And Use Levels

It is approved in the EU at quantum satis (QS), in almost all authorised food categories listed below.

Its application is listed in Group I and separately by E 1200.

The following foods may contain with it (10):

Table-top sweeteners in powder and tablets form

Energy-reduced and low-alcohol beers

Also, it is authorized as a carrier.

http://www.chinafooding.com/Polydextrose