Drug Introduction of Cycloserine Home News Industry News
Drug Introduction of Cycloserine

 Scientific name "D -4-- amino-3 - tetrahydro isoxazolidinone." Formula C3H6N2O2, molecular weight 102.09. White or light yellow crystalline powder. Hygroscopic, odorless, bitter taste. Melting point 155-156 ℃ (decomposition). Soluble in water, slightly soluble in ethanol, slightly soluble in chloroform, ether. Specific rotation [\ alpha] D ^ 23 +116 ° (C = 1.17%, water). Soluble at pH of about 6. With acid or alkali salt. Neutral or acidic solution is not stable, may be 3 - hydroxy - 2 - amino-propionate hydrochloride below as raw material by chlorination, cyclization, split system. Antibiotics, in addition to anti-TB, the Gram-positive bacteria, negative bacteria, rickettsia bacteria also inhibited. Mainly used to treat drug-resistant clinical Mycobacterium tuberculosis infection.

 Cycloserine - Drug Introduction
 Drug Name
 English name Cyloserine
 Other names: cycloserine, neomycin East, oxazole neomycin, neomycin to kill TB, Tai Su ADM, ADM oxygen
 Indications function: the role of anti-tuberculosis than isoniazid, streptomycin weak, but the hard-bacterial resistance, mainly for drug-resistant Mycobacterium tuberculosis infections
 Dosage: 1, the amount of adult 0.5g; children 10mg/kg, 2 service, with half the amount of the first dose
 Points to note: toxic side effects, mainly the nervous system toxicity, gastrointestinal tract may also have anti-fever.
 Drug Description: tablet 0.25g

 Cycloserine - congeners

 Molecular structure of D-cycloserine
 English name: D-Cycloserine
 Synonyms: D-4-Amino-3-isoxazolidinone
 Product Name: D-cycloserine
 Molecular structure
 Molecular formula: C3H6N2O2
 Molecular Weight: 102.09
 CAS No. :68-41-7
 EINECS No. :200 -688-4
 Physical and chemical properties
 Melting point: 147 º C
 Specific rotation: 111 º (C = 5,2 NNAOH)
 Water solubility: soluble

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