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Identification and Toxicological basis of calcium Propionate

Basic Information
Calcium Propionate
Encoding GB 17.005; INS 282
Traits white crystalline powder, melting point above 400 ℃ (decomposition), odorless or with slight special smell. Can be made of monohydrate or trihydrate, plate-like monoclinic crystals, soluble in water (1g about 3mL water soluble), slightly soluble in methanol, ethanol, not soluble in benzene and acetone. 10% aqueous solution of pH equal to 7.4.
 Method by the propionic acid and calcium hydroxide or calcium carbonate reaction. Industry generally use calcium hydroxide as raw materials in 11:50 into the calcium hydroxide suspension tune, add acid reaction, the end of pH7 ~ 8, filtered drying products.

(1) Take 5mL sample solution (1 +10) and 5mL sulfuric acid (1 +9) were hot, with a special release of propionic acid odor. (2 with hydrochloric acid after the platinum wire picks up wet samples, was in a colorless flame red (brick red) color.

Toxicological basis 
1. Oral LD50 3340mg/kg body weight in mice.
2. GRAS FDA 21CFR 181.23; 184.1221.
3. ADI no requirement (FAO / WHO, 1994).
Use of preservatives.

(1) the use of leavening agents should not use calcium propionate, as may be due to calcium carbonate formation and the ability to reduce carbon dioxide.
(2) for the acid-based preservative calcium propionate, in the acidic range of valid: pH5 the following inhibition of fungal best, pH6 significantly reduced when the antimicrobial activity.

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