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Outline of natamycin

Outline
Natamycin is a macrolide antifungal agent multi-olefin, it almost all the antibacterial activity of yeasts and molds are not only able to inhibit the fungus, but also to prevent the production of fungal ADM.

The molecule is a cyclic tetraene with the activity of compounds containing three or more crystal water, and its appearance white (or cream), is a colorless, odorless, crystalline powder, molecular formula C33H47NO13, the molecular weight of 665.73. Slightly soluble in water, methanol, soluble in dilute acid, acetic acid and xylene, formamide, insoluble in most organic solvents. At pH values ​​higher than 9 or less than 3, its solubility will be increased, in most of the PH range of food is very stable. Natamycin has a certain resistance to heat treatment capacity in the dry state is relatively stable and can withstand short-term high-temperature (100 ℃); but because it has a ring chemical structure, are more sensitive to UV, it is not appropriate and sun exposure. The stability of Natamycin activity by the PH value, temperature, light intensity and the impact of oxidants and heavy metals, so the products should be avoided and sulfur oxides and hydrogen compounds and other contacts.

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